McDonald, C R White, N S Farid, N Lai, G Kuperman, J M Bartsch, H Hagler, D J Kesari, S Carter, B S Chen, C C
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Published in
AJNR. American journal of neuroradiology
DTI is being increasingly used to visualize critical white matter tracts adjacent to brain tumors before neurosurgical resection. However, brain tumors, particularly high-grade gliomas, are typically surrounded by regions of FLAIR hyperintensity that include edema, which increase isotropic diffusion, degrading the ability of standard DTI to uncover...
Kothari, Pranay White, Nathan S Farid, Nikdokht Chung, Romy Kuperman, Joshua M Girard, Holly M Shankaranarayanan, Ajit Kesari, Santosh McDonald, Carrie R Dale, Anders M
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Published in
AJNR. American journal of neuroradiology
Antiangiogenic therapies, such as bevacizumab, decrease contrast enhancement and FLAIR hyperintensity in patients with high-grade gliomas in a manner that may not correlate with actual tumor response. This study evaluated the ability of an advanced DWI technique, restriction spectrum imaging, to improve conspicuity within regions of restricted diff...